Aicar is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with Aicar mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
|Aicar Molecular Formula||C9H14N4O5|
|Aicar Molecular weight||258.23|
|Aicar Apperance||Off-White Powder|
|Usage||Pharmaceutical intermediates. For the treatment of cardiovascular diseases|
Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.