Sildenafil / Viagra CAS 171599-83-0 For Sex Enhancer

Name: Sildenafil citrate
CAS No.: 171599-83-0
Formula: C28H38N6O11S
Molecular Weight: 666.70
Synonyms: Piperazine,1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-(9CI);5-[2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;Revatio;
Melting Point: 187-189 °C
Boiling Point: 672.4 °C at 760 mmHg
Flash Point: 360.5 °C
Solubility: insoluble in water, ethanol
Appearance: White solid

 

Description:
 

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.

Rare but serious adverse effects found through postmarketing surveillance include priapism, severe hypotension, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. As a result of these postmarketing reports, in October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss.

 

Applications:

Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.

In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, dyspepsia, nasal congestion and impaired vision, including photophobia and blurred vision.Some sildenafil users have complained of seeing everything tinted blue (cyanopsia).Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that sildenafil could lead to vision impairment in rare cases and a number of studies have linked sildenafil use with nonarteritic anterior ischemic optic neuropathy.

 

Sildenaf Citrate Action

As well as treating impotence, Sildenaf Citrate can also be effective in treating Pulmonary Arterial Hypertension (PAH). Similarly to how it acts to relax muscles of the penis, it relaxes arterial walls; therefore, reducing resistance and pressure in the arteries.

Sildenaf Citrate is solely active in relaxing muscles and increasing blood flow to the heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the body.

 

Sexual dysfunction

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatment for erectile dysfunction, including for men with diabetes mellitus.

 

COA

Items Standard Results
Assay by HPLC: 98% 99.37%
Appearance: White fine powder Complies
Odor & taste: Slight bitter Complies
Mesh size: 100% pass 80mesh Complies
Solubility: Soluble in water Complies
Loss on drying: ≤2.0% 1.15%
Heavy metals PPM: <30ppm Complies
Microbiology:

Total Plate Count:

Yeast & Mold:

E.Coli:

S. Aureus:

Salmonella:

 

<1000cfu/g

<100cfu/g

Negative

Negative

Negative

 

800cfu/g

90cfu/g

Complies

Complies

Complies

Conclusion: Conform with USP 32

 

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s