Anti-Ulcer Agent Powder Famotidine CAS 76824-35-6

Quick Details:

Product name: Famotidine
Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;aminosulfonyl)-;dispronil;famodil;famosan;famoxal
CAS: 76824-35-6
Purity: 99%
MF: C8H15N7O2S3
MW: 337.45
Appearance: White Powder
Usage: Antiinflammatory And An Anti-ulcer Agent

 

Description of Famotidine:

Famotidine, sold under the trade name Pepcid among others is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.

Unlike cimetidine, the first H2 antagonist, famotidine has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs.It was discovered in 1979.

 

COA:

Test Item Analysis Specification Result
Appearance white crystalline powder Conforms
Identification Positive Positive
Loss on drying 0.5% max 0.13%
Residue on ignition 0.1% max 0.05%
Heavy metals 10ppm max Conforms
Chromatographic purity should conform Conforms
Organic volatile impurities should meet the requirements meets the requirements
Assay (Based on dried weight) 98.5-101.0 % 99.51%
Conclusion This commodity complies with the requirements of the U.S.P 31

 

Usage of Famotidine:

1.Relief of heartburn, acid indigestion, and sour stomach
2.Treatment for gastric and duodenal ulcers
3.Treatment for pathologic gastrointestinal hypersecretory conditions such as Zollinger-Ellison syndrome and multiple endocrine adenomas
4.Treatment for gastroesophageal reflux disease (GERD)
5.Treatment for esophagitis
6.Part of a multidrug regimen for Helicobacter pylori eradication, although omeprazole may be somewhat more effective.
7.Prevention of NSAID-induced peptic ulcers.
8.Given to surgery patients before operations to reduce the risk of aspiration pneumonitis.
9.Famotidine is also given to dogs and cats with acid reflux.[15] Famotidine has been used in combination with an H1 antagonist to treat and prevent urticaria caused by an acute allergic reaction.

 

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