Clomifene Citrate

Clomifene Citrate

Name Clomifene Citrate
CAS No 50-41-9
EINECS 200-035-3
Molecular Formula C32H36ClNO8
Molecular Weight 598.08
Melting point 116.5-118°C
Appearance White Crystalline Solid
Standard Enterprise Standard
Purity 99%
Packing 25KG/Drum or as per your requirements
Application An unducer of ovulation

Description:

Clomifene citrate is the commonly referenced brand name for the drug clomiphene citrate. It is not an anabolic steroid, but a prescription drug generally prescribed to women as a fertility aid. This is due to the fact that clomiphene citrate shows a pronounced ability to stimulate ovulation. This is accomplished by blocking/minimizing the effects of estrogen in the body. To be more specific Clomid is chemically a synthetic estrogen with both agonist/antagonist properties, and is very similar in structure and action to Nolvadex. In certain target tissues it can block the ability of estrogen to bind with its corresponding receptor. Its clinical use is therefore to oppose the negative feedback of estrogens on the hypothalamic-pituitary-ovarian axis, which enhances the release of LH and FSH. This of course can help to induce ovulation.

Application:

Clomifene (INN) or clomiphene (USAN) (trademarked as Androxal, Clomid and Omifin) is a selective estrogen receptor modulator (SERM) that has become the most widely prescribed drug for ovulation induction to reverse anovulation or oligoovulation.

Clomifene is useful in those who are infertile due to anovulation or oligoovulation. Evidence is lacking for the use of clomifene in those who are infertile without a known reason. In such cases, studies have observed a clinical pregnancy rate 5.6% per cycle with clomifene treatment vs. 1.3%-4.2% per cycle without treatment.
Clomifene has also been used with other assisted reproductive technology to increase success rates of these other modalities.

As for toxicity and side effects, Clomid is considered a very safe drug. Bodybuilders seldom report any problems, but listed possible side effects do include hot flashes, nausea, dizziness, headaches and temporarily blurred vision.

Such side effects usually only appear in females however, as they feel the effects of estrogen manipulation much more readily than men. While female athletes can clearly gain some benefit from this substance, estrogen manipulation is probably not the most comfortable way to go about cutting up.

Should it still be used for such purposed and side effects do become pronounced, the drug of course is to be discontinued and (at least) a break taken from it.

4.COA:
 

Tests Analysis Standard Results
Identification Conform Conform
Absorbance ≤0.30% Conform
Specific Rotation +39°~ +43° +39.5°
Chromatography Purity Conform Conform
17α-Isomer ≤0.50% 0.40%
Organic Volatile Impurities Conform Conform
Loss On Drying ≤0.50% 0.32%
Residue On Ignition ≤0.10% 0.01%
Assay 97~101% 99.02%
Conclusion Be Conform With USP31 Standard