Purity (HPLC): ≥98.0%
Function: Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH)
That is naturally released from the hypothalamus gland.
Storage: A cool(2~8 °C) & dry place
Appearance: White or slightly yellowish powder White powder
SolubilitySoluble in water or 1% acetic acid at a concentration of 1mg/ml to give a clear, colorless solutionConforms
Identity by HPLCThe retention is same with the reference substanceConforms
Specific Optical Rotation-65.0- -75.0° (c=0.5, 95%HAc)-71.3°
Amino Acid Composition± 10% of theoreticalConforms
Peptide Purity (By HPLC)≥ 98.0% by area integration98.8%
Related Substance (By HPLC)Total Impurities(%) ≤ 2.0% Largest Single Impurity (%) ≤ 1.0%1.2% 0.7%
Acetate Content≤ 15.0%13.8%
Water Content (Karl Fischer)≤ 5.0%1.5%
How does it work:
Gonadorelin is a hormone that is produced naturally by the hypothalamus in the brain. It is also known as gonadotrophin-releasing hormone or GnRH.
Gonadorelin stimulates the pituitary gland in the brain to release the sex hormones luteinising hormone (LH) and follicle stimulating hormone (FSH). In women, FSH stimulates the production of oestrogen and the development of eggs in the ovaries. LH stimulates the ovaries to release an egg (ovulation). In men, LH stimulates the testicles to produce the hormone testosterone and FSH stimulates the testicles to produce sperm.
Gonadorelin is given by injection to check whether the pituitary gland is producing LH and FSH in the correct levels. This can help in the diagnosis of various hormonal disorders, including infertility, delayed puberty and hypogonadism.