CAS No.: 38304-91-5
Molecular Weight: 209.25
Appearance: White crystalline powder
Molecular Formula: C9H15N5O
Standard: USP34 & EP7.0
Minoxidil Certificate of Analysis
|Appearance||White or almost white crystalline||White crystal powder|
|Residue on ignition||≤0.5%||0.05%|
|Loss on drying||≤0.5%||0.15%|
|Organic volatile impurities||Accord with USP34||Accord with USP34|
Minoxidil can used for refractory hypertension and renal hypertension, the antihypertensive effects of hydralazine stronger than that.Mechanism for the K + channel opening, so that vascular smooth muscle. it Is a vasodilator antihypertensive drug classes. Does not cause orthostatic hypotension, no long-term efficacy of medication .
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss).Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure that included hair growth and reversal of male baldness.
Minoxidil needs to be applied twice daily, and may be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. To achieve maximum effect, the solution should be in contact with the scalp for at least 4 hours before allowing hair to get wet.Minoxidil stimulates hair follicles and growth, but does not reduce dihydrotestosterone (DHT) or the enzyme responsible for its accumulation around the hair follicle, 5-alpha reductase, which is the primary mediator of male pattern baldness in genetically susceptible individuals.Therefore, when treatment is stopped, the DHT has its expected effect of shrinking and ultimately destroying the genetically predisposed hair follicles. There are multiple types of minoxidil applications: dropper, foam and spray.
Minoxidil Side Effects:
Minoxidil is generally well tolerated, but common side effects include burning or irritation of the eye, itching, redness or irritation at the treated area, as well as unwanted hair growth elsewhere on the body.