Sildenafil Citrate

Sildenafil Citrate

Name sildenafil citrate
CAS No 171599-83-0
Synonyms Sildenafil citrate; viagra
Assay 98%
MF C28H38N6O11S
MW 666.7

 

Usage:  An orally active selective type 5 cGMP phosphodiesterase inhibitor Biological Activity :Orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC 50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro.

 

Specification:

Name Sildenafil Citrate
Appearance White crystalline powder
Loss on drying ≤1.0% 0.3%
Acidity 3.0-5.0 4.1
Residue on ignition ≤0.1% 0.05%
Heavy metals ≤20ppm Complies
Relevant impurity ≤0.5% 0.02%
Methanol ≤0.3% 0.025%
Methylene dichloride ≤0.06% 0.013%
N,N-Dimethyl formamide ≤0.088% Not detected
Assay(on dried basis) ≥98% 98.4%

 

HPLC: